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A reaction with another antigout drug, allopurinol, may cause a rash. The addition of allopurinol may help to protect the renal tubules from long-term damage due to uric acid crystallization. Do not use this medication if you are allergic to didanosine, or if you are also taking allopurinol (Zyloprim) or ribavirin (Rebetol, Ribasphere, Copegus Virazole). {06} {35} {36} However, the uricosuric agents are less toxic than allopurinol and should be considered for use when appropriate {37}. The total amount of allopurinol is usually not more than 800 mg a day.
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